Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal anti-tumor immunity

Gut microbiota, specifically gut bacteria, are critical for effective immune checkpoint blockade therapy (ICT) for cancer. The mechanisms by which gut microbiota augment extraintestinal anti-cancer immune responses, however, are largely unknown. Here, we find that ICT induces the translocation of sp...

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Detalles Bibliográficos
Autores principales: Choi, Yongbin, Lichterman, Jake N., Coughlin, Laura A., Poulides, Nicole, Li, Wenling, Del Valle, Priscilla, Palmer, Suzette N., Gan, Shuheng, Kim, Jiwoong, Zhan, Xiaowei, Gao, Yajing, Evers, Bret M., Hooper, Lora V., Pasare, Chandrashekhar, Koh, Andrew Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080670/
https://www.ncbi.nlm.nih.gov/pubmed/36867675
http://dx.doi.org/10.1126/sciimmunol.abo2003

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