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Modular Oxidation of Cytosine Modifications and Their Application in Direct and Quantitative Sequencing of 5-Hydroxymethylcytosine

[Image: see text] Selective, efficient, and controllable oxidation of cytosine modifications is valuable for epigenetic analyses, yet only limited progress has been made. Here, we present two modular chemical oxidation reactions: conversion of 5-hydroxymethylcytosine (5hmC) into 5-formylcytosine (5f...

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Detalles Bibliográficos
Autores principales:	Xu, Haiqi, Chen, Jinfeng, Cheng, Jingfei, Kong, Linzhen, Chen, Xiufei, Inoue, Masato, Liu, Yibin, Kriaucionis, Skirmantas, Zhao, Meiping, Song, Chun-Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080677/ https://www.ncbi.nlm.nih.gov/pubmed/36961225 http://dx.doi.org/10.1021/jacs.3c01663

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