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Leptin ameliorates Aβ1-42-induced Alzheimer’s disease by suppressing inflammation via activating p-Akt signaling pathway
BACKGROUND: Alzheimer’s disease (AD) is characterized by progressive neuronal loss, cognitive disorder, and memory decline. Leptin has been reported to have a neuroprotective effect on neurodegenerative diseases. OBJECTIVE: Our aim was to investigate whether intraperitoneal injection of leptin has a...
Autores principales: | Lu, Lin, Fu, Zijuan, Wu, Bing, Zhang, Dongsen, Wang, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080705/ https://www.ncbi.nlm.nih.gov/pubmed/37035120 http://dx.doi.org/10.1515/tnsci-2022-0270 |
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