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Reading and writing of mRNA m(6)A modification orchestrate maternal-to-zygotic transition in mice

N(6)-methyladenosine (m(6)A) modification has been shown to regulate RNA metabolism. Here, we investigate m(6)A dynamics during maternal-to-zygotic transition (MZT) in mice through multi-omic analysis. Our results show that m(6)A can be maternally inherited or de novo gained after fertilization. Int...

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Detalles Bibliográficos
Autores principales: Zhu, Wencheng, Ding, Yufeng, Meng, Juan, Gu, Lei, Liu, Wenjun, Li, Li, Chen, Hongyu, Wang, Yining, Li, Ziyi, Li, Chen, Sun, Yidi, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080794/
https://www.ncbi.nlm.nih.gov/pubmed/37024923
http://dx.doi.org/10.1186/s13059-023-02918-9