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Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation

BACKGROUND: Eukaryotic cells can rapidly adjust their transcriptional profile in response to molecular needs. Such dynamic regulation is, in part, achieved through epigenetic modifications and selective incorporation of histone variants into chromatin. H3.3 is the ancestral H3 variant with key roles...

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Detalles Bibliográficos
Autores principales: Nabeel-Shah, Syed, Garg, Jyoti, Ashraf, Kanwal, Jeyapala, Renu, Lee, Hyunmin, Petrova, Alexandra, Burns, James D., Pu, Shuye, Zhang, Zhaolei, Greenblatt, Jack F., Pearlman, Ronald E., Lambert, Jean-Philippe, Fillingham, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080907/
https://www.ncbi.nlm.nih.gov/pubmed/37024975
http://dx.doi.org/10.1186/s13072-023-00484-9