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Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis
Objectives: Acute kidney injury (AKI) is associated with increased mortality among coronavirus disease 2019 (COVID-19) patients. This meta-analysis aimed to identify risk factors for the development of AKI in patients with COVID-19. Methods: A systematic literature search was conducted in PubMed and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081062/ https://www.ncbi.nlm.nih.gov/pubmed/37021610 http://dx.doi.org/10.1080/0886022X.2023.2170809 |
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author | Zhang, Jialing Pang, Qi Zhou, Ting Meng, Jiali Dong, Xingtong Wang, Zhe Zhang, Aihua |
author_facet | Zhang, Jialing Pang, Qi Zhou, Ting Meng, Jiali Dong, Xingtong Wang, Zhe Zhang, Aihua |
author_sort | Zhang, Jialing |
collection | PubMed |
description | Objectives: Acute kidney injury (AKI) is associated with increased mortality among coronavirus disease 2019 (COVID-19) patients. This meta-analysis aimed to identify risk factors for the development of AKI in patients with COVID-19. Methods: A systematic literature search was conducted in PubMed and EMBASE from 1 December 2019 to 1 January 2023. Due to significant study heterogeneity, meta-analyses were conducted using random-effects models. Meta-regression and sensitivity analysis were also performed. Results: A total of 153,600 COVID-19 patients from 39 studies were included, and 28,003 patients developed AKI. By meta-analysis, we discovered that age, male sex, obesity, black race, invasive ventilation, and the use of diuretics, steroids and vasopressors, in addition to comorbidities such as hypertension, congestive heart failure, chronic kidney disease, acute respiratory distress syndrome, and diabetes, were significant risk factors for COVID-19-associated AKI. Conclusions: Early detection of these risk factors is essential to reduce the incidence of AKI and improve the prognosis of COVID-19 patients. |
format | Online Article Text |
id | pubmed-10081062 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-100810622023-04-08 Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis Zhang, Jialing Pang, Qi Zhou, Ting Meng, Jiali Dong, Xingtong Wang, Zhe Zhang, Aihua Ren Fail State-of-the-Art Review Objectives: Acute kidney injury (AKI) is associated with increased mortality among coronavirus disease 2019 (COVID-19) patients. This meta-analysis aimed to identify risk factors for the development of AKI in patients with COVID-19. Methods: A systematic literature search was conducted in PubMed and EMBASE from 1 December 2019 to 1 January 2023. Due to significant study heterogeneity, meta-analyses were conducted using random-effects models. Meta-regression and sensitivity analysis were also performed. Results: A total of 153,600 COVID-19 patients from 39 studies were included, and 28,003 patients developed AKI. By meta-analysis, we discovered that age, male sex, obesity, black race, invasive ventilation, and the use of diuretics, steroids and vasopressors, in addition to comorbidities such as hypertension, congestive heart failure, chronic kidney disease, acute respiratory distress syndrome, and diabetes, were significant risk factors for COVID-19-associated AKI. Conclusions: Early detection of these risk factors is essential to reduce the incidence of AKI and improve the prognosis of COVID-19 patients. Taylor & Francis 2023-04-06 /pmc/articles/PMC10081062/ /pubmed/37021610 http://dx.doi.org/10.1080/0886022X.2023.2170809 Text en © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent. |
spellingShingle | State-of-the-Art Review Zhang, Jialing Pang, Qi Zhou, Ting Meng, Jiali Dong, Xingtong Wang, Zhe Zhang, Aihua Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
title | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
title_full | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
title_fullStr | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
title_full_unstemmed | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
title_short | Risk factors for acute kidney injury in COVID-19 patients: an updated systematic review and meta-analysis |
title_sort | risk factors for acute kidney injury in covid-19 patients: an updated systematic review and meta-analysis |
topic | State-of-the-Art Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081062/ https://www.ncbi.nlm.nih.gov/pubmed/37021610 http://dx.doi.org/10.1080/0886022X.2023.2170809 |
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