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Chalcone: A potential scaffold for NLRP3 inflammasome inhibitors

Overactivated NLRP3 inflammasome has been shown to associate with an increasing number of disease conditions. Activation of the NLRP3 inflammasome results in caspase-1-catalyzed formation of active pro-inflammatory cytokines (IL-1β and IL-18) resulting in pyroptosis. The multi-protein composition of...

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Detalles Bibliográficos
Autores principales:	Thapa, Pritam, Upadhyay, Sunil P., Singh, Vikas, Boinpelly, Varun C., Zhou, Jianping, Johnson, David K., Gurung, Prajwal, Lee, Eung Seok, Sharma, Ram, Sharma, Mukut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081147/ https://www.ncbi.nlm.nih.gov/pubmed/37033416 http://dx.doi.org/10.1016/j.ejmcr.2022.100100

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