FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates

The molecular and cellular mechanisms driving the enhanced therapeutic ratio of ultra-high dose-rate radiotherapy (FLASH-RT) over slower conventional (CONV-RT) radiotherapy dose-rate remain to be elucidated. However, attenuated DNA damage and transient oxygen depletion are among several proposed mod...

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Detalles Bibliográficos
Autores principales: Barghouth, Paul G., Melemenidis, Stavros, Montay-Gruel, Pierre, Ollivier, Jonathan, Viswanathan, Vignesh, Jorge, Patrik G., Soto, Luis A., Lau, Brianna C., Sadeghi, Cheyenne, Edlabadkar, Anushka, Manjappa, Rakesh, Wang, Jinghui, Le Bouteiller, Marie, Surucu, Murat, Yu, Amy, Bush, Karl, Skinner, Lawrie, Maxim, Peter G., Loo, Billy W., Limoli, Charles L., Vozenin, Marie-Catherine, Frock, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081175/
https://www.ncbi.nlm.nih.gov/pubmed/37034651
http://dx.doi.org/10.1101/2023.03.27.534408

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