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Multiple repeat regions within mouse DUX recruit chromatin regulators to facilitate an embryonic gene expression program

The embryonic transcription factor DUX regulates chromatin opening and gene expression in totipotent cleavage-stage mouse embryos, and its expression in embryonic stem cells promotes their conversion to 2-cell embryo-like cells (2CLCs) with extraembryonic potential. However, little is known regardin...

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Detalles Bibliográficos
Autores principales: Smith, Christina M., Grow, Edward J., Shadle, Sean C., Cairns, Bradley R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081216/
https://www.ncbi.nlm.nih.gov/pubmed/37034731
http://dx.doi.org/10.1101/2023.03.29.534786

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