Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes

Development of vaccines and therapeutics that are broadly effective against known and emergent coronaviruses is an urgent priority. Current strategies for developing pan-coronavirus countermeasures have largely focused on the receptor binding domain (RBD) and S2 regions of the coronavirus Spike prot...

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Detalles Bibliográficos
Autores principales: Hurtado, Jonathan, Rogers, Thomas F., Jaffe, David B., Adams, Bruce A., Bangaru, Sandhya, Garcia, Elijah, Capozzola, Tazio, Messmer, Terrence, Sharma, Pragati, Song, Ge, Beutler, Nathan, He, Wanting, Dueker, Katharina, Musharrafieh, Rami, Stubbington, Michael J.T., Burton, Dennis R., Andrabi, Raiees, Ward, Andrew B., McDonnell, Wyatt J., Briney, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081229/
https://www.ncbi.nlm.nih.gov/pubmed/37034676
http://dx.doi.org/10.1101/2023.03.28.534602

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