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A head-to-head comparison of two DREADD agonists for suppressing operant behavior in rats via VTA dopamine neuron inhibition

RATIONALE: Designer receptors exclusively activated by designer drugs (DREADDs) are a tool for “remote control” of defined neuronal populations during behavior. These receptors are inert unless bound by an experimenter-administered designer drug, most commonly clozapine-n-oxide (CNO). However, quest...

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Detalles Bibliográficos
Autores principales: Lawson, Kate A, Ruiz, Christina M, Mahler, Stephen V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081263/
https://www.ncbi.nlm.nih.gov/pubmed/37034819
http://dx.doi.org/10.1101/2023.03.27.534429