Cargando…

Colocalization of blood cell traits GWAS associations and variation in PU.1 genomic occupancy prioritizes causal noncoding regulatory variants

Genome-wide association studies (GWAS) have uncovered numerous trait-associated loci across the human genome, most of which are located in noncoding regions, making interpretations difficult. Moreover, causal variants are hard to statistically fine-map at many loci because of widespread linkage dise...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Raehoon, Bulyk, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081269/
https://www.ncbi.nlm.nih.gov/pubmed/37034747
http://dx.doi.org/10.1101/2023.03.29.534582

Ejemplares similares