Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression

Tumors acquire an increased ability to obtain and metabolize nutrients. Here, we engineered and implanted adipocytes to outcompete tumors for nutrients and show that they can substantially reduce cancer progression. Growing cells or xenografts from several cancers (breast, colon, pancreas, prostate)...

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Detalles Bibliográficos
Autores principales: Nguyen, Hai P., Sheng, Rory, Murray, Elizabeth, Ito, Yusuke, Bruck, Michael, Biellak, Cassidy, An, Kelly, Lynce, Filipa, Dillon, Deborah A., Magbanua, Mark Jesus M., Huppert, Laura A., Hammerlindl, Heinz, Esserman, Laura, Rosenbluth, Jennifer M., Ahituv, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081280/
https://www.ncbi.nlm.nih.gov/pubmed/37034710
http://dx.doi.org/10.1101/2023.03.28.534564

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