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Maternal exposure to metal components of PM2.5 and low birth weight in New Mexico, USA

Infants with low birth weight (LBW) are more likely to have health problems than normal weight infants. In studies examining the associations between particulate matter (PM) exposures and LBW, there is a tendency to focus on PM(2.5) as a whole. However, insufficient information is available regardin...

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Autores principales: Huang, Yanhong, Gong, Xi, Liu, Lin, Luo, Li, Leng, Shuguang, Lin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081375/
https://www.ncbi.nlm.nih.gov/pubmed/37034648
http://dx.doi.org/10.21203/rs.3.rs-2666605/v1
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author Huang, Yanhong
Gong, Xi
Liu, Lin
Luo, Li
Leng, Shuguang
Lin, Yan
author_facet Huang, Yanhong
Gong, Xi
Liu, Lin
Luo, Li
Leng, Shuguang
Lin, Yan
author_sort Huang, Yanhong
collection PubMed
description Infants with low birth weight (LBW) are more likely to have health problems than normal weight infants. In studies examining the associations between particulate matter (PM) exposures and LBW, there is a tendency to focus on PM(2.5) as a whole. However, insufficient information is available regarding the effects of different components of PM(2.5) on birth weight. This study identified the associations between maternal exposure to 10 metal components of PM(2.5) and LBW in offspring based on small area (divided by population size) level data in New Mexico, USA, from 2012 to 2016. This study used a pruned feed-forward neural network (pruned-FNN) approach to estimate the annual average exposure index to each metal component in each small area. The linear regression model was employed to examine the association between maternal PM(2.5) metal exposures and LBW rate in small areas, adjusting for the female percentage and race/ethnicity compositions, marriage status and educational level in the population. An interquartile range increase in maternal exposure to mercury and chromium of PM(2.5) increased LBW rate by 0.43% (95% confidence interval (CI): 0.18%−0.68%) and 0.63% (95% CI: 0.15%−1.12%), respectively. These findings suggest that maternal exposure to metal components of air pollutants may increase the risk of LBW in offspring. With no similar studies in New Mexico, this study also posed great importance because of a higher LBW rate in New Mexico than the national average. These findings provide critical information to inform further epidemiological, biological, and toxicological studies.
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spelling pubmed-100813752023-04-08 Maternal exposure to metal components of PM2.5 and low birth weight in New Mexico, USA Huang, Yanhong Gong, Xi Liu, Lin Luo, Li Leng, Shuguang Lin, Yan Res Sq Article Infants with low birth weight (LBW) are more likely to have health problems than normal weight infants. In studies examining the associations between particulate matter (PM) exposures and LBW, there is a tendency to focus on PM(2.5) as a whole. However, insufficient information is available regarding the effects of different components of PM(2.5) on birth weight. This study identified the associations between maternal exposure to 10 metal components of PM(2.5) and LBW in offspring based on small area (divided by population size) level data in New Mexico, USA, from 2012 to 2016. This study used a pruned feed-forward neural network (pruned-FNN) approach to estimate the annual average exposure index to each metal component in each small area. The linear regression model was employed to examine the association between maternal PM(2.5) metal exposures and LBW rate in small areas, adjusting for the female percentage and race/ethnicity compositions, marriage status and educational level in the population. An interquartile range increase in maternal exposure to mercury and chromium of PM(2.5) increased LBW rate by 0.43% (95% confidence interval (CI): 0.18%−0.68%) and 0.63% (95% CI: 0.15%−1.12%), respectively. These findings suggest that maternal exposure to metal components of air pollutants may increase the risk of LBW in offspring. With no similar studies in New Mexico, this study also posed great importance because of a higher LBW rate in New Mexico than the national average. These findings provide critical information to inform further epidemiological, biological, and toxicological studies. American Journal Experts 2023-03-31 /pmc/articles/PMC10081375/ /pubmed/37034648 http://dx.doi.org/10.21203/rs.3.rs-2666605/v1 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. https://creativecommons.org/licenses/by/4.0/License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Article
Huang, Yanhong
Gong, Xi
Liu, Lin
Luo, Li
Leng, Shuguang
Lin, Yan
Maternal exposure to metal components of PM2.5 and low birth weight in New Mexico, USA
title Maternal exposure to metal components of PM2.5 and low birth weight in New Mexico, USA
title_full Maternal exposure to metal components of PM2.5 and low birth weight in New Mexico, USA
title_fullStr Maternal exposure to metal components of PM2.5 and low birth weight in New Mexico, USA
title_full_unstemmed Maternal exposure to metal components of PM2.5 and low birth weight in New Mexico, USA
title_short Maternal exposure to metal components of PM2.5 and low birth weight in New Mexico, USA
title_sort maternal exposure to metal components of pm2.5 and low birth weight in new mexico, usa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081375/
https://www.ncbi.nlm.nih.gov/pubmed/37034648
http://dx.doi.org/10.21203/rs.3.rs-2666605/v1
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