Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes

Tobacco use disorder (TUD) is the most prevalent substance use disorder in the world. Genetic factors influence smoking behaviors, and although strides have been made using genome-wide association studies (GWAS) to identify risk variants, the majority of variants identified have been for nicotine co...

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Detalles Bibliográficos
Autores principales: Toikumo, Sylvanus, Jennings, Mariela V, Pham, Benjamin K, Lee, Hyunjoon, Mallard, Travis T, Bianchi, Sevim B, Meredith, John J, Vilar-Ribó, Laura, Xu, Heng, Hatoum, Alexander S, Johnson, Emma C, Pazdernik, Vanessa, Jinwala, Zeal, Pakala, Shreya R, Leger, Brittany S, Niarchou, Maria, Ehinmowo, Michael, Jenkins, Greg D, Batzler, Anthony, Pendegraft, Richard, Palmer, Abraham A, Zhou, Hang, Biernacka, Joanna M, Coombes, Brandon J, Gelernter, Joel, Xu, Ke, Hancock, Dana B, Cox, Nancy J, Smoller, Jordan W, Davis, Lea K, Justice, Amy C, Kranzler, Henry R, Kember, Rachel L, Sanchez-Roige, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081388/
https://www.ncbi.nlm.nih.gov/pubmed/37034728
http://dx.doi.org/10.1101/2023.03.27.23287713

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