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The Impact of Body Mass Index and Medical Conditions on Home-based Anal Self-Sampling

PURPOSE. Self-sampling is increasingly being used in screening programs, yet no studies to date have examined the impact of bodily characteristics on self-sampling experiences. Our objective was to assess whether body mass index (BMI) and physical disability were associated with anal self-sampling d...

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Autores principales: Nitkowski, Jenna, Fernandez, Maria E., Ridolfi, Tim, Chiao, Elizabeth, Giuliano, Anna R., Schick, Vanessa, Swartz, Michael D., Smith, Jennifer S., Nyitray, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081437/
https://www.ncbi.nlm.nih.gov/pubmed/37034807
http://dx.doi.org/10.21203/rs.3.rs-2748914/v1
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author Nitkowski, Jenna
Fernandez, Maria E.
Ridolfi, Tim
Chiao, Elizabeth
Giuliano, Anna R.
Schick, Vanessa
Swartz, Michael D.
Smith, Jennifer S.
Nyitray, Alan G.
author_facet Nitkowski, Jenna
Fernandez, Maria E.
Ridolfi, Tim
Chiao, Elizabeth
Giuliano, Anna R.
Schick, Vanessa
Swartz, Michael D.
Smith, Jennifer S.
Nyitray, Alan G.
author_sort Nitkowski, Jenna
collection PubMed
description PURPOSE. Self-sampling is increasingly being used in screening programs, yet no studies to date have examined the impact of bodily characteristics on self-sampling experiences. Our objective was to assess whether body mass index (BMI) and physical disability were associated with anal self-sampling difficulty. METHODS. We recruited sexual minority men (SMM) and trans persons in Milwaukee, Wisconsin to participate in an anal cancer screening study. Between January 2020 and August 2022, 240 participants were randomized to a home (n=120) or clinic (n=120) screening arm. Home participants received a mailed at-home anal self-sampling kit and were asked to attend a baseline clinic visit where biometric measurements were collected. Participants were asked to complete a survey about their experience with the kit. This research utilizes data from participants who used the kit and completed a baseline clinic visit and post-swab survey (n=82). We assessed the impact of BMI and physical disability on reported body or swab positioning difficulty. RESULTS. Most participants reported no or little difficulty with body positioning (90.3%) or swab positioning (82.9%). Higher BMI was significantly associated with greater reported difficulty with body positioning (aOR=1.10, 95% CI 1.003–1.20, p=.04) and swab positioning (aOR=1.11, 95% CI 1.02–1.20, p=.01). Physical disability was not significantly associated with body or swab positioning difficulty. Specimen adequacy did not differ by BMI category (p=.76) or physical disability (p=.88). CONCLUSION. Anal self-sampling may be a viable option to reach obese persons who may be more likely to avoid screening due to weight-related barriers.
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spelling pubmed-100814372023-04-08 The Impact of Body Mass Index and Medical Conditions on Home-based Anal Self-Sampling Nitkowski, Jenna Fernandez, Maria E. Ridolfi, Tim Chiao, Elizabeth Giuliano, Anna R. Schick, Vanessa Swartz, Michael D. Smith, Jennifer S. Nyitray, Alan G. Res Sq Article PURPOSE. Self-sampling is increasingly being used in screening programs, yet no studies to date have examined the impact of bodily characteristics on self-sampling experiences. Our objective was to assess whether body mass index (BMI) and physical disability were associated with anal self-sampling difficulty. METHODS. We recruited sexual minority men (SMM) and trans persons in Milwaukee, Wisconsin to participate in an anal cancer screening study. Between January 2020 and August 2022, 240 participants were randomized to a home (n=120) or clinic (n=120) screening arm. Home participants received a mailed at-home anal self-sampling kit and were asked to attend a baseline clinic visit where biometric measurements were collected. Participants were asked to complete a survey about their experience with the kit. This research utilizes data from participants who used the kit and completed a baseline clinic visit and post-swab survey (n=82). We assessed the impact of BMI and physical disability on reported body or swab positioning difficulty. RESULTS. Most participants reported no or little difficulty with body positioning (90.3%) or swab positioning (82.9%). Higher BMI was significantly associated with greater reported difficulty with body positioning (aOR=1.10, 95% CI 1.003–1.20, p=.04) and swab positioning (aOR=1.11, 95% CI 1.02–1.20, p=.01). Physical disability was not significantly associated with body or swab positioning difficulty. Specimen adequacy did not differ by BMI category (p=.76) or physical disability (p=.88). CONCLUSION. Anal self-sampling may be a viable option to reach obese persons who may be more likely to avoid screening due to weight-related barriers. American Journal Experts 2023-03-31 /pmc/articles/PMC10081437/ /pubmed/37034807 http://dx.doi.org/10.21203/rs.3.rs-2748914/v1 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. https://creativecommons.org/licenses/by/4.0/License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Article
Nitkowski, Jenna
Fernandez, Maria E.
Ridolfi, Tim
Chiao, Elizabeth
Giuliano, Anna R.
Schick, Vanessa
Swartz, Michael D.
Smith, Jennifer S.
Nyitray, Alan G.
The Impact of Body Mass Index and Medical Conditions on Home-based Anal Self-Sampling
title The Impact of Body Mass Index and Medical Conditions on Home-based Anal Self-Sampling
title_full The Impact of Body Mass Index and Medical Conditions on Home-based Anal Self-Sampling
title_fullStr The Impact of Body Mass Index and Medical Conditions on Home-based Anal Self-Sampling
title_full_unstemmed The Impact of Body Mass Index and Medical Conditions on Home-based Anal Self-Sampling
title_short The Impact of Body Mass Index and Medical Conditions on Home-based Anal Self-Sampling
title_sort impact of body mass index and medical conditions on home-based anal self-sampling
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081437/
https://www.ncbi.nlm.nih.gov/pubmed/37034807
http://dx.doi.org/10.21203/rs.3.rs-2748914/v1
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