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Radiodermatitis: severity, predictive factors and discontinuation of radiotherapy in patients with anal and rectal cancer

OBJECTIVE: to determine the prevalence of radiodermatitis, severity grades and predictive factors of its occurrence in patients with anal and rectal cancer followed up by the nursing consultation, and to analyze the association of severity grades of radiodermatitis with temporary radiotherapy interr...

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Detalles Bibliográficos
Autores principales: Bastos, Larissa Jucá Dantas, Lanzillotti, Regina Serrão, Brandão, Marcos Antônio Gomes, da Silva, Rafael Celestino, Simões, Fabiana Verdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Universidade de São Paulo, Escola de Enfermagem 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081625/
https://www.ncbi.nlm.nih.gov/pubmed/35723900
http://dx.doi.org/10.1590/1980-220X-REEUSP-2021-0378en
Descripción
Sumario:OBJECTIVE: to determine the prevalence of radiodermatitis, severity grades and predictive factors of its occurrence in patients with anal and rectal cancer followed up by the nursing consultation, and to analyze the association of severity grades of radiodermatitis with temporary radiotherapy interruption. METHOD: a quantitative, cross-sectional and retrospective study, carried out with 112 medical records of patients with anal and rectal cancer undergoing curative radiotherapy followed up in the nursing consultation. Data were collected using a form and analyzed using analytical and inferential statistics. RESULTS: 99.1% of patients had radiodermatitis, 34.8% of which were severe. The predictive factors were female sex, age greater than 65 years, anal canal tumor, treatment with cobalt device and IMRT technique. Treatment interruption occurred in 13% of patients, associated with severe radiodermatitis. CONCLUSION: there was a high prevalence of radiodermatitis, mainly severe, which resulted in treatment interruption.