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Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response

Immune checkpoint inhibitors (ICIs) targeting PD-L1 immunotherapy are state-of-the-art treatments for advanced non–small cell lung cancer (NSCLC). However, the treatment response of certain patients with NSCLC is unsatisfactory because of an unfavorable tumor microenvironment (TME) and poor permeabi...

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Detalles Bibliográficos
Autores principales:	Lin, Chia-Yi, Huang, Kuo-Yen, Kao, Shih-Han, Lin, Ming-Shiu, Lin, Chih-Chien, Yang, Shuenn-Chen, Chung, Wei-Chia, Chang, Ya-Hsuan, Chein, Rong-Jie, Yang, Pan-Chyr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081850/ https://www.ncbi.nlm.nih.gov/pubmed/37027467 http://dx.doi.org/10.1126/sciadv.ade9944

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