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Evolution of TOP1 and TOP1MT Topoisomerases in Chordata

Type IB topoisomerases relax the torsional stress associated with DNA metabolism in the nucleus and mitochondria and constitute important molecular targets of anticancer drugs. Vertebrates stand out among eukaryotes by having two Type IB topoisomerases acting specifically in the nucleus (TOP1) and m...

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Detalles Bibliográficos
Autores principales:	Moreira, Filipa, Arenas, Miguel, Videira, Arnaldo, Pereira, Filipe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081982/ https://www.ncbi.nlm.nih.gov/pubmed/36651963 http://dx.doi.org/10.1007/s00239-022-10091-z

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