Enhancer of zeste homolog 2 promotes renal fibrosis after acute kidney injury by inducing epithelial-mesenchymal transition and activation of M2 macrophage polarization

Long-term follow-up data indicates that 1/4 patients with acute kidney injury (AKI) will develop to chronic kidney disease (CKD). Our previous studies have demonstrated that enhancer of zeste homolog 2 (EZH2) played an important role in AKI and CKD. However, the role and mechanisms of EZH2 in AKI-to...

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Detalles Bibliográficos
Autores principales: Zhou, Xun, Chen, Hui, Hu, Yan, Ma, Xiaoyan, Li, Jinqing, Shi, Yingfeng, Tao, Min, Wang, Yi, Zhong, Qin, Yan, Danying, Zhuang, Shougang, Liu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081989/
https://www.ncbi.nlm.nih.gov/pubmed/37029114
http://dx.doi.org/10.1038/s41419-023-05782-4

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