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Aberrant somatic calcium channel function in cNurr1 and LRRK2-G2019S mice

In Parkinson’s disease (PD), axons of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) degenerate before their cell bodies. Calcium influx during pacemaker firing might contribute to neuronal loss, but it is not known if dysfunctions of voltage-gated calcium channels (VGCCs) occ...

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Detalles Bibliográficos
Autores principales:	Skiteva, Olga, Yao, Ning, Mantas, Ioannis, Zhang, Xiaoqun, Perlmann, Thomas, Svenningsson, Per, Chergui, Karima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082048/ https://www.ncbi.nlm.nih.gov/pubmed/37029193 http://dx.doi.org/10.1038/s41531-023-00500-5

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