An International Expert Delphi Consensus on Defining Textbook Outcome in Liver Surgery (TOLS)

To reach global expert consensus on the definition of TOLS in minimally invasive and open liver resection among renowned international expert liver surgeons using a modified Delphi method. BACKGROUND: Textbook outcome is a novel composite measure combining the most desirable postoperative outcomes i...

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Detalles Bibliográficos
Autores principales: Görgec, Burak, Benedetti Cacciaguerra, Andrea, Pawlik, Timothy M., Aldrighetti, Luca A., Alseidi, Adnan A., Cillo, Umberto, Kokudo, Norihiro, Geller, David A., Wakabayashi, Go, Asbun, Horacio J., Besselink, Marc G., Cherqui, Daniel, Cheung, Tan To, Clavien, Pierre-Alain, Conrad, Claudius, D’Hondt, Mathieu, Dagher, Ibrahim, Dervenis, Christos, Devar, John, Dixon, Elijah, Edwin, Bjørn, Efanov, Mikhail, Ettore, Giuseppe M., Ferrero, Alessandro, Fondevilla, Constantino, Fuks, David, Giuliante, Felice, Han, Ho-Seong, Honda, Goro, Imventarza, Oscar, Kooby, David A., Lodge, Peter, Lopez-Ben, Santiago, Machado, Marcel A., Marques, Hugo P., O’Rourke, Nick, Pekolj, Juan, Pinna, Antonio D., Portolani, Nazario, Primrose, John, Rotellar, Fernando, Ruzzenente, Andrea, Schadde, Erik, Siriwardena, Ajith K., Smadi, Sameer, Soubrane, Olivier, Tanabe, Kenneth K., Teh, Catherine S.C., Torzilli, Guido, Van Gulik, Thomas M., Vivarelli, Marco, Wigmore, Stephen J., Abu Hilal, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082050/
https://www.ncbi.nlm.nih.gov/pubmed/35946822
http://dx.doi.org/10.1097/SLA.0000000000005668
Descripción
Sumario:To reach global expert consensus on the definition of TOLS in minimally invasive and open liver resection among renowned international expert liver surgeons using a modified Delphi method. BACKGROUND: Textbook outcome is a novel composite measure combining the most desirable postoperative outcomes into one single measure and representing the ideal postoperative course. Despite a recently developed international definition of Textbook Outcome in Liver Surgery (TOLS), a standardized and expert consensus-based definition is lacking. METHODS: This international, consensus-based, qualitative study used a Delphi process to achieve consensus on the definition of TOLS. The survey comprised 6 surgical domains with a total of 26 questions on individual surgical outcome variables. The process included 4 rounds of online questionnaires. Consensus was achieved when a threshold of at least 80% agreement was reached. The results from the Delphi rounds were used to establish an international definition of TOLS. RESULTS: In total, 44 expert liver surgeons from 22 countries and all 3 major international hepato-pancreato-biliary associations completed round 1. Forty-two (96%), 41 (98%), and 41 (98%) of the experts participated in round 2, 3, and 4, respectively. The TOLS definition derived from the consensus process included the absence of intraoperative grade ≥2 incidents, postoperative bile leakage grade B/C, postoperative liver failure grade B/C, 90-day major postoperative complications, 90-day readmission due to surgery-related major complications, 90-day/in-hospital mortality, and the presence of R0 resection margin. CONCLUSIONS: This is the first study providing an international expert consensus-based definition of TOLS for minimally invasive and open liver resections by the use of a formal Delphi consensus approach. TOLS may be useful in assessing patient-level hospital performance and carrying out international comparisons between centers with different clinical practices to further improve patient outcomes.

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