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SpaDecon: cell-type deconvolution in spatial transcriptomics with semi-supervised learning

Spatially resolved transcriptomics (SRT) has advanced our understanding of the spatial patterns of gene expression, but the lack of single-cell resolution in spatial barcoding-based SRT hinders the inference of specific locations of individual cells. To determine the spatial distribution of cell typ...

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Detalles Bibliográficos
Autores principales: Coleman, Kyle, Hu, Jian, Schroeder, Amelia, Lee, Edward B., Li, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082183/
https://www.ncbi.nlm.nih.gov/pubmed/37029267
http://dx.doi.org/10.1038/s42003-023-04761-x