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Phytochemical Composition and Bioassay on Iranian Teucrium Polium Extracts against Anopheles Stephensi (Diptera: Culicidae)

BACKGROUND: Anopheles stephensi is an important malaria vector mosquito in Iran and other western Asian countries. In many human communities, plant products have been used traditionally instead of synthetic pesticides for mosquito control due to their minimal hazardous effects. Teucrium polium, know...

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Autores principales: Ghafari, Saeedeh, Tahghighi, Azar, Shamakhte, Khadijeh, Alipour, Hamzeh, Maleki-Ravasan, Naseh, Nateghpour, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082410/
https://www.ncbi.nlm.nih.gov/pubmed/37038505
http://dx.doi.org/10.18502/jad.v16i2.11804
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author Ghafari, Saeedeh
Tahghighi, Azar
Shamakhte, Khadijeh
Alipour, Hamzeh
Maleki-Ravasan, Naseh
Nateghpour, Mehdi
author_facet Ghafari, Saeedeh
Tahghighi, Azar
Shamakhte, Khadijeh
Alipour, Hamzeh
Maleki-Ravasan, Naseh
Nateghpour, Mehdi
author_sort Ghafari, Saeedeh
collection PubMed
description BACKGROUND: Anopheles stephensi is an important malaria vector mosquito in Iran and other western Asian countries. In many human communities, plant products have been used traditionally instead of synthetic pesticides for mosquito control due to their minimal hazardous effects. Teucrium polium, known popularly as felty germander, has been introduced in Persian Medicine (PM) as an insect repellent from a long time ago. METHODS: The present study was undertaken to evaluate repellent and larvicidal activity of dichloromethane (DCMETP) and ethanolic extracts (EE-TP) of T. polium against An. stephensi under laboratory conditions. The possible chemical components of the extracts were also investigated through gas chromatography/mass spectrometry (GC-MS) technique. RESULTS: Based on the results, DCME-TP showed better repellent activity than EE-TP with 56.67 and 28.33 % protection, respectively. Larvicidal activity of DCME-TP with 49.41% mortality was also higher than EE-TP (20.24%). The main identified constituents of DCME-TP were long chain alkanes, phenol, aromatic ester, oxaspiro and triterpenoid. While phenolic and aliphatic acid were only the identified components in EE-TP. It is notable that lupeol was detected in DCME of T. polium for the first time. CONCLUSION: DCME-TP can be considered as a new herbal candidate to control An. stephensi mosquitoes. Further studies are required on this extract for the fractionation and identification of the active compounds, and the evaluation of their bioactivity in the laboratory and field.
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spelling pubmed-100824102023-04-09 Phytochemical Composition and Bioassay on Iranian Teucrium Polium Extracts against Anopheles Stephensi (Diptera: Culicidae) Ghafari, Saeedeh Tahghighi, Azar Shamakhte, Khadijeh Alipour, Hamzeh Maleki-Ravasan, Naseh Nateghpour, Mehdi J Arthropod Borne Dis Original Article BACKGROUND: Anopheles stephensi is an important malaria vector mosquito in Iran and other western Asian countries. In many human communities, plant products have been used traditionally instead of synthetic pesticides for mosquito control due to their minimal hazardous effects. Teucrium polium, known popularly as felty germander, has been introduced in Persian Medicine (PM) as an insect repellent from a long time ago. METHODS: The present study was undertaken to evaluate repellent and larvicidal activity of dichloromethane (DCMETP) and ethanolic extracts (EE-TP) of T. polium against An. stephensi under laboratory conditions. The possible chemical components of the extracts were also investigated through gas chromatography/mass spectrometry (GC-MS) technique. RESULTS: Based on the results, DCME-TP showed better repellent activity than EE-TP with 56.67 and 28.33 % protection, respectively. Larvicidal activity of DCME-TP with 49.41% mortality was also higher than EE-TP (20.24%). The main identified constituents of DCME-TP were long chain alkanes, phenol, aromatic ester, oxaspiro and triterpenoid. While phenolic and aliphatic acid were only the identified components in EE-TP. It is notable that lupeol was detected in DCME of T. polium for the first time. CONCLUSION: DCME-TP can be considered as a new herbal candidate to control An. stephensi mosquitoes. Further studies are required on this extract for the fractionation and identification of the active compounds, and the evaluation of their bioactivity in the laboratory and field. Tehran University of Medical Sciences 2022-06-30 /pmc/articles/PMC10082410/ /pubmed/37038505 http://dx.doi.org/10.18502/jad.v16i2.11804 Text en Copyright © 2022 The Authors. Published by Tehran University of Medical Sciences https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Article
Ghafari, Saeedeh
Tahghighi, Azar
Shamakhte, Khadijeh
Alipour, Hamzeh
Maleki-Ravasan, Naseh
Nateghpour, Mehdi
Phytochemical Composition and Bioassay on Iranian Teucrium Polium Extracts against Anopheles Stephensi (Diptera: Culicidae)
title Phytochemical Composition and Bioassay on Iranian Teucrium Polium Extracts against Anopheles Stephensi (Diptera: Culicidae)
title_full Phytochemical Composition and Bioassay on Iranian Teucrium Polium Extracts against Anopheles Stephensi (Diptera: Culicidae)
title_fullStr Phytochemical Composition and Bioassay on Iranian Teucrium Polium Extracts against Anopheles Stephensi (Diptera: Culicidae)
title_full_unstemmed Phytochemical Composition and Bioassay on Iranian Teucrium Polium Extracts against Anopheles Stephensi (Diptera: Culicidae)
title_short Phytochemical Composition and Bioassay on Iranian Teucrium Polium Extracts against Anopheles Stephensi (Diptera: Culicidae)
title_sort phytochemical composition and bioassay on iranian teucrium polium extracts against anopheles stephensi (diptera: culicidae)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082410/
https://www.ncbi.nlm.nih.gov/pubmed/37038505
http://dx.doi.org/10.18502/jad.v16i2.11804
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