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The potential of Panaxnotoginseng against COVID-19 infection

The COVID-19 pandemic has changed the world and has presented the scientific community with unprecedented challenges. Infection is associated with overproduction of proinflammatory cytokines secondary to hyperactivation of the innate immune response, inducing a cytokine storm and triggering multiorg...

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Detalles Bibliográficos
Autores principales: Hu, Yeye, He, Ziliang, Zhang, Wei, Niu, Zhiqiang, Wang, Yanting, Zhang, Ji, Shen, Ting, Cheng, Hong, Hu, Weicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082468/
https://www.ncbi.nlm.nih.gov/pubmed/37362082
http://dx.doi.org/10.1016/j.jgr.2023.04.002
Descripción
Sumario:The COVID-19 pandemic has changed the world and has presented the scientific community with unprecedented challenges. Infection is associated with overproduction of proinflammatory cytokines secondary to hyperactivation of the innate immune response, inducing a cytokine storm and triggering multiorgan failure and significant morbidity/mortality. No specific treatment is yet available. For thousands of years, Panax notoginseng has been used to treat various infectious diseases. Experimental evidence of P. notoginseng utility in terms of alleviating the cytokine storm, especially the cascade, and improving post-COVID-19 symptoms, suggests that P. notoginseng may serve as a valuable adjunct treatment for COVID-19 infection.