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IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma

Medulloblastoma (MB) is the most common pediatric brain malignancy and is divided into four molecularly distinct subgroups: WNT, Sonic Hedgehog (SHHp53mut and SHHp53wt), Group 3, and Group 4. Previous reports suggest that SHH MB features a unique tumor microenvironment compared with other MB groups....

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Detalles Bibliográficos
Autores principales:	Kunhiraman, Haritha, McSwain, Leon, Shahab, Shubin W., Gershon, Timothy R., MacDonald, Tobey J., Kenney, Anna Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082504/ https://www.ncbi.nlm.nih.gov/pubmed/37029430 http://dx.doi.org/10.1186/s40478-023-01557-2

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