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Calcium oxalate crystal-induced secretome derived from proximal tubular cells, not that from distal tubular cells, induces renal fibroblast activation

BACKGROUND: Kidney stone disease (KSD) is commonly accompanied with renal fibrosis, characterized by accumulation and reorganization of extracellular matrix (ECM). During fibrogenesis, resident renal fibroblasts are activated to become myofibroblasts that actively produce ECM. However, such fibrobla...

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Detalles Bibliográficos
Autores principales:	Noonin, Chadanat, Itsaranawet, Tanakorn, Thongboonkerd, Visith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082508/ https://www.ncbi.nlm.nih.gov/pubmed/37031165 http://dx.doi.org/10.1186/s40001-023-01109-3

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