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Refractive index based optically transparent biosensor device design for early detection of coronavirus
For the quick detection of the new Coronavirus (COVID-19), a highly sensitive D-shaped gold-coated surface Plasmon resonance (SPR) biosensor is presented. The COVID-19 virus may be quickly and accurately identified using the SPR-based biosensor, which is essential for halting the spread of this excr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082629/ https://www.ncbi.nlm.nih.gov/pubmed/37065724 http://dx.doi.org/10.1007/s11082-023-04788-8 |
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author | Balamurugan, A. M. Parvin, Tarunnum Alsalem, Kasim Abdul Jabar Ibrahim, Sobhy M. |
author_facet | Balamurugan, A. M. Parvin, Tarunnum Alsalem, Kasim Abdul Jabar Ibrahim, Sobhy M. |
author_sort | Balamurugan, A. M. |
collection | PubMed |
description | For the quick detection of the new Coronavirus (COVID-19), a highly sensitive D-shaped gold-coated surface Plasmon resonance (SPR) biosensor is presented. The COVID-19 virus may be quickly and accurately identified using the SPR-based biosensor, which is essential for halting the spread of this excruciating epidemic. The suggested biosensor is used for detection of the IBV i.e. infectious bronchitis viruses contaminated cell that belongs to the family of COVID-19 having a refractive index of − 0.96, − 0.97, − 0.98, − 0.99, − 1 that is observed with the change in EID concentration. Some important optical parameter variations are examined in the investigation process. Multiphysics version 5.3 with the Finite element method is used for the proposed biosensor. The proposed sensor depicts maximum wavelength sensitivity of 40,141.76 nm/RIU. Some other parameters such as confinement loss, crosstalk, and insertion loss are also analyzed for the proposed sensor. The reported minimum insertion loss for the refractive index (RI) − 1 is 2.9 dB. Simple design, good sensitivity, and lower value of losses make the proposed sensor proficient for the detection of infectious bronchitis viruses belonging to COVID-19. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-10082629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-100826292023-04-11 Refractive index based optically transparent biosensor device design for early detection of coronavirus Balamurugan, A. M. Parvin, Tarunnum Alsalem, Kasim Abdul Jabar Ibrahim, Sobhy M. Opt Quantum Electron Article For the quick detection of the new Coronavirus (COVID-19), a highly sensitive D-shaped gold-coated surface Plasmon resonance (SPR) biosensor is presented. The COVID-19 virus may be quickly and accurately identified using the SPR-based biosensor, which is essential for halting the spread of this excruciating epidemic. The suggested biosensor is used for detection of the IBV i.e. infectious bronchitis viruses contaminated cell that belongs to the family of COVID-19 having a refractive index of − 0.96, − 0.97, − 0.98, − 0.99, − 1 that is observed with the change in EID concentration. Some important optical parameter variations are examined in the investigation process. Multiphysics version 5.3 with the Finite element method is used for the proposed biosensor. The proposed sensor depicts maximum wavelength sensitivity of 40,141.76 nm/RIU. Some other parameters such as confinement loss, crosstalk, and insertion loss are also analyzed for the proposed sensor. The reported minimum insertion loss for the refractive index (RI) − 1 is 2.9 dB. Simple design, good sensitivity, and lower value of losses make the proposed sensor proficient for the detection of infectious bronchitis viruses belonging to COVID-19. GRAPHICAL ABSTRACT: [Image: see text] Springer US 2023-04-08 2023 /pmc/articles/PMC10082629/ /pubmed/37065724 http://dx.doi.org/10.1007/s11082-023-04788-8 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Balamurugan, A. M. Parvin, Tarunnum Alsalem, Kasim Abdul Jabar Ibrahim, Sobhy M. Refractive index based optically transparent biosensor device design for early detection of coronavirus |
title | Refractive index based optically transparent biosensor device design for early detection of coronavirus |
title_full | Refractive index based optically transparent biosensor device design for early detection of coronavirus |
title_fullStr | Refractive index based optically transparent biosensor device design for early detection of coronavirus |
title_full_unstemmed | Refractive index based optically transparent biosensor device design for early detection of coronavirus |
title_short | Refractive index based optically transparent biosensor device design for early detection of coronavirus |
title_sort | refractive index based optically transparent biosensor device design for early detection of coronavirus |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082629/ https://www.ncbi.nlm.nih.gov/pubmed/37065724 http://dx.doi.org/10.1007/s11082-023-04788-8 |
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