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Refractive index based optically transparent biosensor device design for early detection of coronavirus

For the quick detection of the new Coronavirus (COVID-19), a highly sensitive D-shaped gold-coated surface Plasmon resonance (SPR) biosensor is presented. The COVID-19 virus may be quickly and accurately identified using the SPR-based biosensor, which is essential for halting the spread of this excr...

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Autores principales: Balamurugan, A. M., Parvin, Tarunnum, Alsalem, Kasim Abdul Jabar, Ibrahim, Sobhy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082629/
https://www.ncbi.nlm.nih.gov/pubmed/37065724
http://dx.doi.org/10.1007/s11082-023-04788-8
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author Balamurugan, A. M.
Parvin, Tarunnum
Alsalem, Kasim Abdul Jabar
Ibrahim, Sobhy M.
author_facet Balamurugan, A. M.
Parvin, Tarunnum
Alsalem, Kasim Abdul Jabar
Ibrahim, Sobhy M.
author_sort Balamurugan, A. M.
collection PubMed
description For the quick detection of the new Coronavirus (COVID-19), a highly sensitive D-shaped gold-coated surface Plasmon resonance (SPR) biosensor is presented. The COVID-19 virus may be quickly and accurately identified using the SPR-based biosensor, which is essential for halting the spread of this excruciating epidemic. The suggested biosensor is used for detection of the IBV i.e. infectious bronchitis viruses contaminated cell that belongs to the family of COVID-19 having a refractive index of − 0.96, − 0.97, − 0.98, − 0.99, − 1 that is observed with the change in EID concentration. Some important optical parameter variations are examined in the investigation process. Multiphysics version 5.3 with the Finite element method is used for the proposed biosensor. The proposed sensor depicts maximum wavelength sensitivity of 40,141.76 nm/RIU. Some other parameters such as confinement loss, crosstalk, and insertion loss are also analyzed for the proposed sensor. The reported minimum insertion loss for the refractive index (RI) − 1 is 2.9 dB. Simple design, good sensitivity, and lower value of losses make the proposed sensor proficient for the detection of infectious bronchitis viruses belonging to COVID-19. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-100826292023-04-11 Refractive index based optically transparent biosensor device design for early detection of coronavirus Balamurugan, A. M. Parvin, Tarunnum Alsalem, Kasim Abdul Jabar Ibrahim, Sobhy M. Opt Quantum Electron Article For the quick detection of the new Coronavirus (COVID-19), a highly sensitive D-shaped gold-coated surface Plasmon resonance (SPR) biosensor is presented. The COVID-19 virus may be quickly and accurately identified using the SPR-based biosensor, which is essential for halting the spread of this excruciating epidemic. The suggested biosensor is used for detection of the IBV i.e. infectious bronchitis viruses contaminated cell that belongs to the family of COVID-19 having a refractive index of − 0.96, − 0.97, − 0.98, − 0.99, − 1 that is observed with the change in EID concentration. Some important optical parameter variations are examined in the investigation process. Multiphysics version 5.3 with the Finite element method is used for the proposed biosensor. The proposed sensor depicts maximum wavelength sensitivity of 40,141.76 nm/RIU. Some other parameters such as confinement loss, crosstalk, and insertion loss are also analyzed for the proposed sensor. The reported minimum insertion loss for the refractive index (RI) − 1 is 2.9 dB. Simple design, good sensitivity, and lower value of losses make the proposed sensor proficient for the detection of infectious bronchitis viruses belonging to COVID-19. GRAPHICAL ABSTRACT: [Image: see text] Springer US 2023-04-08 2023 /pmc/articles/PMC10082629/ /pubmed/37065724 http://dx.doi.org/10.1007/s11082-023-04788-8 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Balamurugan, A. M.
Parvin, Tarunnum
Alsalem, Kasim Abdul Jabar
Ibrahim, Sobhy M.
Refractive index based optically transparent biosensor device design for early detection of coronavirus
title Refractive index based optically transparent biosensor device design for early detection of coronavirus
title_full Refractive index based optically transparent biosensor device design for early detection of coronavirus
title_fullStr Refractive index based optically transparent biosensor device design for early detection of coronavirus
title_full_unstemmed Refractive index based optically transparent biosensor device design for early detection of coronavirus
title_short Refractive index based optically transparent biosensor device design for early detection of coronavirus
title_sort refractive index based optically transparent biosensor device design for early detection of coronavirus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082629/
https://www.ncbi.nlm.nih.gov/pubmed/37065724
http://dx.doi.org/10.1007/s11082-023-04788-8
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