Pyrazole-sulfonamide scaffold featuring dual-tail strategy as apoptosis inducers in colon cancer

Dual-tail strategy has been successfully utilized in the development of novel carbonic anhydrase IX (CA IX) inhibitors. Herein we adopted this approach in the design and synthesis of a series of novel pyridine sulfonamide-pyrazole hybrid scaffold mimicking dual-tail inhibitors of CA IX. A library of...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Hazek, Reham M. M., Zaher, Nashwa H., Emam, Hagar E. S., El-Gazzar, Marwa G., Khalil, Amira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082777/
https://www.ncbi.nlm.nih.gov/pubmed/37031294
http://dx.doi.org/10.1038/s41598-023-32820-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082777/
https://www.ncbi.nlm.nih.gov/pubmed/37031294
http://dx.doi.org/10.1038/s41598-023-32820-0

Ejemplares similares