Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells

Radiotherapy is the standard adjuvant treatment for glioma patients; however, the efficacy is limited by radioresistance. The function of Interleukin-1 receptor associated kinase 1 (IRAK1) in tumorigenesis and radioresistance remains to be elucidated. IRAK1 expression and its correlation with progno...

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Detalles Bibliográficos
Autores principales: Li, Jing, Sun, Yuchen, Zhao, Xu, Ma, Yuan, Xie, Yuchen, Liu, Siqi, Hui, Beina, Shi, Xiaobo, Sun, Xuanzi, Zhang, Xiaozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082800/
https://www.ncbi.nlm.nih.gov/pubmed/37031183
http://dx.doi.org/10.1038/s41419-023-05732-0

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