A nonstop thrill ride from genes to the assembly of the T3SS injectisome

The type three secretion system (T3SS) is a membrane-anchored nano-machine utilized by many pathogenic bacteria to inject effector proteins and thus take control of host cells. In a recent article, Kaval et al. reveal a striking colocalization of a T3SS-encoding locus, its transcriptional activators...

Descripción completa

Detalles Bibliográficos
Autores principales: Fishov, Itzhak, Namboodiri, Sharanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082841/
https://www.ncbi.nlm.nih.gov/pubmed/37031218
http://dx.doi.org/10.1038/s41467-023-37753-w
_version_ 1785021398165487616
author Fishov, Itzhak
Namboodiri, Sharanya
author_facet Fishov, Itzhak
Namboodiri, Sharanya
author_sort Fishov, Itzhak
collection PubMed
description The type three secretion system (T3SS) is a membrane-anchored nano-machine utilized by many pathogenic bacteria to inject effector proteins and thus take control of host cells. In a recent article, Kaval et al. reveal a striking colocalization of a T3SS-encoding locus, its transcriptional activators, protein products, and the complete structure at the cell membrane, which they claim provides evidence for a mechanism known as ‘transertion’.
format Online
Article
Text
id pubmed-10082841
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-100828412023-04-10 A nonstop thrill ride from genes to the assembly of the T3SS injectisome Fishov, Itzhak Namboodiri, Sharanya Nat Commun Comment The type three secretion system (T3SS) is a membrane-anchored nano-machine utilized by many pathogenic bacteria to inject effector proteins and thus take control of host cells. In a recent article, Kaval et al. reveal a striking colocalization of a T3SS-encoding locus, its transcriptional activators, protein products, and the complete structure at the cell membrane, which they claim provides evidence for a mechanism known as ‘transertion’. Nature Publishing Group UK 2023-04-08 /pmc/articles/PMC10082841/ /pubmed/37031218 http://dx.doi.org/10.1038/s41467-023-37753-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Fishov, Itzhak
Namboodiri, Sharanya
A nonstop thrill ride from genes to the assembly of the T3SS injectisome
title A nonstop thrill ride from genes to the assembly of the T3SS injectisome
title_full A nonstop thrill ride from genes to the assembly of the T3SS injectisome
title_fullStr A nonstop thrill ride from genes to the assembly of the T3SS injectisome
title_full_unstemmed A nonstop thrill ride from genes to the assembly of the T3SS injectisome
title_short A nonstop thrill ride from genes to the assembly of the T3SS injectisome
title_sort nonstop thrill ride from genes to the assembly of the t3ss injectisome
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082841/
https://www.ncbi.nlm.nih.gov/pubmed/37031218
http://dx.doi.org/10.1038/s41467-023-37753-w
work_keys_str_mv AT fishovitzhak anonstopthrillridefromgenestotheassemblyofthet3ssinjectisome
AT namboodirisharanya anonstopthrillridefromgenestotheassemblyofthet3ssinjectisome
AT fishovitzhak nonstopthrillridefromgenestotheassemblyofthet3ssinjectisome
AT namboodirisharanya nonstopthrillridefromgenestotheassemblyofthet3ssinjectisome

Ejemplares similares