Cargando…

Effects of epigenetic age acceleration on kidney function: a Mendelian randomization study

BACKGROUND: Previous studies have reported cross-sectional associations between measures of epigenetic age acceleration (EAA) and kidney function phenotypes. However, the temporal and potentially causal relationships between these variables remain unclear. We conducted a bidirectional two-sample Men...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Yang, Sun, Xiao, Huang, Zhijie, Zhang, Ruiyuan, Li, Changwei, Anderson, Amanda H., Lash, James P., Kelly, Tanika N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10082992/ https://www.ncbi.nlm.nih.gov/pubmed/37031184 http://dx.doi.org/10.1186/s13148-023-01476-y

Ejemplares similares

Effects of iron homeostasis on epigenetic age acceleration: a two-sample Mendelian randomization study
por: Wang, Zhihao, et al.
Publicado: (2023)

A longitudinal study of polygenic score and cognitive function decline considering baseline cognitive function, lifestyle behaviors, and diabetes among middle-aged and older US adults
por: Liu, Tingting, et al.
Publicado: (2023)

Life-Course Associations between Blood Pressure-Related Polygenic Risk Scores and Hypertension in the Bogalusa Heart Study
por: Sun, Xiao, et al.
Publicado: (2022)

Causal association of epigenetic aging and osteoporosis: a bidirectional Mendelian randomization study
por: Liang, Xinyu, et al.
Publicado: (2023)

Mendelian randomization supports causality between overweight status and accelerated aging
por: Chen, Zong, et al.
Publicado: (2023)

Causality between heart failure and epigenetic age: a bidirectional Mendelian randomization study
por: Zhang, Fengjun, et al.
Publicado: (2023)

The Mendelian disorders of the epigenetic machinery
por: Bjornsson, Hans Tomas
Publicado: (2015)

Causal association of epigenetic aging and COVID-19 severity and susceptibility: A bidirectional Mendelian randomization study
por: Xu, Wenchang, et al.
Publicado: (2022)

Impairment of kidney function and kidney cancer: A bidirectional Mendelian randomization study
por: Lin, Yifei, et al.
Publicado: (2022)

Serum bilirubin and kidney function: a Mendelian randomization study
por: Park, Sehoon, et al.
Publicado: (2022)

Review of mendelian randomization studies on age at natural menopause
por: Zhang, Xiao, et al.
Publicado: (2023)

Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation
por: Luperchio, Teresa Romeo, et al.
Publicado: (2021)

Accelerated epigenetic aging in Down syndrome
por: Horvath, Steve, et al.
Publicado: (2015)

Accelerated epigenetic aging in Werner syndrome
por: Maierhofer, Anna, et al.
Publicado: (2017)

Contributions of obesity to kidney health and disease: insights from Mendelian randomization and the human kidney transcriptomics
por: Xu, Xiaoguang, et al.
Publicado: (2021)

Kidney damage on fertility and pregnancy: A Mendelian randomization
por: Ren, Jin, et al.
Publicado: (2023)

Epigenetic mutation load is weakly correlated with epigenetic age acceleration
por: Yan, Qi, et al.
Publicado: (2020)

Can we apply the Mendelian randomization methodology without considering epigenetic effects?
por: Ogbuanu, Ikechukwu U, et al.
Publicado: (2009)

Effect of women’s fertility and sexual development on epigenetic clock: Mendelian randomization study
por: Zhang, Boxin, et al.
Publicado: (2023)

High social status males experience accelerated epigenetic aging in wild baboons
por: Anderson, Jordan A, et al.
Publicado: (2021)

The causal effect of obesity on diabetic retinopathy: A two-sample Mendelian randomization study
por: Zheng, Changwei, et al.
Publicado: (2023)

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study
por: Morales Berstein, Fernanda, et al.
Publicado: (2022)

Effects of Selenium on Chronic Kidney Disease: A Mendelian Randomization Study
por: Fu, Shaojie, et al.
Publicado: (2022)

Age at menarche and lung function: a Mendelian randomization study
por: Gill, Dipender, et al.
Publicado: (2017)

Epigenetics of cognition and behavior: insights from Mendelian disorders of epigenetic machinery
por: Ng, Rowena, et al.
Publicado: (2023)

Systematic underestimation of the epigenetic clock and age acceleration in older subjects
por: El Khoury, Louis Y., et al.
Publicado: (2019)

Olfactory Malformations in Mendelian Disorders of the Epigenetic Machinery
por: Aleo, Sebastiano, et al.
Publicado: (2020)

Association of Adverse Childhood Experiences With Accelerated Epigenetic Aging in Midlife
por: Kim, Kyeezu, et al.
Publicado: (2023)

Exposure to Violence Accelerates Epigenetic Aging in Children
por: Jovanovic, Tanja, et al.
Publicado: (2017)

Epigenetic age acceleration and clinical outcomes in gliomas
por: Zheng, Chunlei, et al.
Publicado: (2020)

Association of cardiovascular health and epigenetic age acceleration
por: Pottinger, Tess D., et al.
Publicado: (2021)

Associations between epigenetic age acceleration and infertility
por: Lee, Yunsung, et al.
Publicado: (2022)

Accelerated epigenetic aging in newborns with Down syndrome
por: Xu, Keren, et al.
Publicado: (2022)

Epigenetic aging in cows is accelerated by milk production
por: Ratan, Prashansa, et al.
Publicado: (2023)

Mendelian randomization reveals causal effects of kidney function on various biochemical parameters
por: Park, Sehoon, et al.
Publicado: (2022)

Effects of blood pressure and antihypertensive drugs on osteoarthritis: a mendelian randomized study
por: Zhang, Yinzhen, et al.
Publicado: (2023)

Causal effect of gut microbiota on DNA methylation phenotypic age acceleration: a two-sample Mendelian randomization study
por: Huang, Yedong, et al.
Publicado: (2023)

Mendelian Randomization
por: Burgess, Stephen
Publicado: (2015)

Infant's DNA Methylation Age at Birth and Epigenetic Aging Accelerators
por: Javed, Ruheena, et al.
Publicado: (2016)

Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals
por: Nevalainen, Tapio, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_g1br082ofk9h38s9a1qcu1kf9q