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Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis

INTRODUCTION: Aspirin is commonly used for the primary and secondary prevention of cardiovascular disease and stroke. Controversy exists concerning whether and when is the optimal time to stop aspirin before spinal surgery. Previous studies on this topic mainly focused on patients who received thora...

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Autores principales: Chung Wong, Yu, Kit Lau, Tsun, Wang Chau, Wai, On Kwok, Kin, Wai Law, Sheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society for Spine Surgery and Related Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083087/
https://www.ncbi.nlm.nih.gov/pubmed/37041877
http://dx.doi.org/10.22603/ssrr.2022-0163
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author Chung Wong, Yu
Kit Lau, Tsun
Wang Chau, Wai
On Kwok, Kin
Wai Law, Sheung
author_facet Chung Wong, Yu
Kit Lau, Tsun
Wang Chau, Wai
On Kwok, Kin
Wai Law, Sheung
author_sort Chung Wong, Yu
collection PubMed
description INTRODUCTION: Aspirin is commonly used for the primary and secondary prevention of cardiovascular disease and stroke. Controversy exists concerning whether and when is the optimal time to stop aspirin before spinal surgery. Previous studies on this topic mainly focused on patients who received thoracolumbar spine surgeries. There are only a few literatures concerning the safety of aspirin use in cervical spine surgery patients. METHODS: This pilot study recruited patients who received cervical laminoplasty from January 2010 to December 2021. The operation time, intraoperative blood loss, and postoperative complications of the patients who had taken aspirin during the perioperative period were compared with age, sex, and comorbidity-matched control patients. Propensity score matching was utilized in the selection of control to minimize bias. RESULTS: Twenty-one patients who have received cervical laminoplasty while taking aspirin during the perioperative period were included. The control group included 21 age, sex, and comorbidity-matched patients who have not taken aspirin. The operation time and intraoperative and postoperative blood loss were higher in patients taking aspirin but were not statistically significant. There was no statistically significant difference in the wound infection rate. No case of epidural hematoma was found. CONCLUSIONS: In patients undergoing cervical laminoplasty, a continuation of aspirin is safe and does not increase the difficulty of the surgery, wound complication, or hemorrhage.
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spelling pubmed-100830872023-04-10 Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis Chung Wong, Yu Kit Lau, Tsun Wang Chau, Wai On Kwok, Kin Wai Law, Sheung Spine Surg Relat Res Original Article INTRODUCTION: Aspirin is commonly used for the primary and secondary prevention of cardiovascular disease and stroke. Controversy exists concerning whether and when is the optimal time to stop aspirin before spinal surgery. Previous studies on this topic mainly focused on patients who received thoracolumbar spine surgeries. There are only a few literatures concerning the safety of aspirin use in cervical spine surgery patients. METHODS: This pilot study recruited patients who received cervical laminoplasty from January 2010 to December 2021. The operation time, intraoperative blood loss, and postoperative complications of the patients who had taken aspirin during the perioperative period were compared with age, sex, and comorbidity-matched control patients. Propensity score matching was utilized in the selection of control to minimize bias. RESULTS: Twenty-one patients who have received cervical laminoplasty while taking aspirin during the perioperative period were included. The control group included 21 age, sex, and comorbidity-matched patients who have not taken aspirin. The operation time and intraoperative and postoperative blood loss were higher in patients taking aspirin but were not statistically significant. There was no statistically significant difference in the wound infection rate. No case of epidural hematoma was found. CONCLUSIONS: In patients undergoing cervical laminoplasty, a continuation of aspirin is safe and does not increase the difficulty of the surgery, wound complication, or hemorrhage. The Japanese Society for Spine Surgery and Related Research 2022-10-28 /pmc/articles/PMC10083087/ /pubmed/37041877 http://dx.doi.org/10.22603/ssrr.2022-0163 Text en Copyright © 2023 The Japanese Society for Spine Surgery and Related Research https://creativecommons.org/licenses/by-nc-nd/4.0/Spine Surgery and Related Research is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Chung Wong, Yu
Kit Lau, Tsun
Wang Chau, Wai
On Kwok, Kin
Wai Law, Sheung
Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis
title Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis
title_full Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis
title_fullStr Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis
title_full_unstemmed Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis
title_short Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis
title_sort safety of continuing aspirin use in cervical laminoplasty: a propensity score-matched analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083087/
https://www.ncbi.nlm.nih.gov/pubmed/37041877
http://dx.doi.org/10.22603/ssrr.2022-0163
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