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Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus

A simple and robust cell culture system is essential for generating authentic SARS-CoV-2 stocks for evaluation of viral pathogenicity, screening of antiviral compounds, and preparation of inactivated vaccines. Evidence suggests that Vero E6, a cell line commonly used in the field to grow SARS-CoV-2,...

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Detalles Bibliográficos
Autores principales: Chen, Da-Yuan, Turcinovic, Jacquelyn, Feng, Shuchen, Kenney, Devin J., Chin, Chue Vin, Choudhary, Manish C., Conway, Hasahn L., Semaan, Marc, Close, Brianna J., Tavares, Alexander H., Seitz, Scott, Khan, Nazimuddin, Kapell, Sebastian, Crossland, Nicholas A., Li, Jonathan Z., Douam, Florian, Baker, Susan C., Connor, John H., Saeed, Mohsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083141/
https://www.ncbi.nlm.nih.gov/pubmed/37095858
http://dx.doi.org/10.1016/j.isci.2023.106634