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Subunit vaccines with a saponin-based adjuvant boost humoral and cellular immunity to MERS coronavirus

Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks have constituted a public health issue with drastic mortality higher than 34%, necessitating the development of an effective vaccine. During MERS-CoV infection, the trimeric spike protein on the viral envelope is primarily responsible...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Chieh, Algaissi, Abdullah, Lai, Chia-Chun, Chang, Chun-Kai, Lin, Jr-Shiuan, Wang, Yi-Shiang, Chang, Bo-Hau, Chang, Yu-Chiuan, Chen, Wei-Ting, Fan, Yong-Qing, Peng, Bi‐Hung, Chao, Chih-Yu, Tzeng, Shiou-Ru, Liang, Pi-Hui, Sung, Wang-Chou, Hu, Alan Yung-Chih, Chang, Shin C., Chang, Ming-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083212/
https://www.ncbi.nlm.nih.gov/pubmed/37085450
http://dx.doi.org/10.1016/j.vaccine.2023.04.006