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Advances in CRISPR/Cas gene therapy for inborn errors of immunity

Inborn errors of immunity (IEIs) are a group of inherited disorders caused by mutations in the protein-coding genes involved in innate and/or adaptive immunity. Hematopoietic stem cell transplantation (HSCT) is a mainstay definitive therapy for many severe IEIs. However, the lack of HLA-matched dono...

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Detalles Bibliográficos
Autores principales:	Liu, Xinyi, Li, Guanglei, Liu, Yin, Zhou, Fuling, Huang, Xingxu, Li, Kui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083256/ https://www.ncbi.nlm.nih.gov/pubmed/37051232 http://dx.doi.org/10.3389/fimmu.2023.1111777

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