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FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress

INTRODUCTION: The impairment of blood-brain barrier (BBB) is one of the key contributors to maternal inflammation induced brain damage in offspring. Our previous studies showed Fibrinogen-like protein 2 (FGL2) deficiency alleviated maternal inflammation induced perinatal brain damage. However, its r...

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Detalles Bibliográficos
Autores principales: Huang, Lianjing, Zhan, Di, Xing, Ying, Yan, Yaqin, Li, Qing, Zhang, Jingyi, Li, Sujuan, Ning, Qin, Zhang, Cai, Luo, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083319/
https://www.ncbi.nlm.nih.gov/pubmed/37051251
http://dx.doi.org/10.3389/fimmu.2023.1157027

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