Toward high-throughput engineering techniques for improving CAR intracellular signaling domains

Chimeric antigen receptors (CAR) are generated by linking extracellular antigen recognition domains with one or more intracellular signaling domains derived from the T-cell receptor complex or various co-stimulatory receptors. The choice and relative positioning of signaling domains help to determin...

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Detalles Bibliográficos
Autores principales: Butler, Savannah E., Hartman, Colin J., Huang, Yina H., Ackerman, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083361/
https://www.ncbi.nlm.nih.gov/pubmed/37051270
http://dx.doi.org/10.3389/fbioe.2023.1101122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083361/
https://www.ncbi.nlm.nih.gov/pubmed/37051270
http://dx.doi.org/10.3389/fbioe.2023.1101122

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