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Alpha-linolenic acid pretreatment alleviates NETs-induced alveolar macrophage pyroptosis by inhibiting pyrin inflammasome activation in a mouse model of sepsis-induced ALI/ARDS

BACKGROUND: Neutrophil extracellular traps (NETs) can cause acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) by inducing macrophage pyroptosis. The purpose of this study was to find out whether pretreatment of alpha-linolenic acid (ALA) could inhibit NETs-induced macrophage pyropto...

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Detalles Bibliográficos
Autores principales:	Liu, Chenchen, Zhou, Yu, Tu, Qing, Yao, Liangfang, Li, Jinbao, Yang, Zhongwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083395/ https://www.ncbi.nlm.nih.gov/pubmed/37051243 http://dx.doi.org/10.3389/fimmu.2023.1146612

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