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Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes

2,3,5,6-Tetramethylpyrazine (TMP) as an active ingredient extracted from a traditional Chinese herbal medicine Ligusticum chuanxiong Hort. has been proved to penetrate blood-brain barrier (BBB) and show neuroprotective effects on cerebral ischemia. However, whether TMP could regulate astrocytic reac...

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Detalles Bibliográficos
Autores principales: Feng, Xue-feng, Li, Ming-cong, Lin, Zi-yue, Li, Man-zhong, Lu, Yun, Zhuang, Yu-ming, Lei, Jian-feng, Wang, Lei, Zhao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083399/
https://www.ncbi.nlm.nih.gov/pubmed/37051111
http://dx.doi.org/10.3389/fncel.2023.1125412