Disruption of energetic and dynamic base pairing cooperativity in DNA duplexes by an abasic site

DNA duplex stability arises from cooperative interactions between multiple adjacent nucleotides that favor base pairing and stacking when formed as a continuous stretch rather than individually. Lesions and nucleobase modifications alter this stability in complex manners that remain challenging to u...

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Detalles Bibliográficos
Autores principales: Ashwood, Brennan, Jones, Michael S., Ferguson, Andrew L., Tokmakoff, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083564/
https://www.ncbi.nlm.nih.gov/pubmed/36976762
http://dx.doi.org/10.1073/pnas.2219124120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083564/
https://www.ncbi.nlm.nih.gov/pubmed/36976762
http://dx.doi.org/10.1073/pnas.2219124120

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