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Altered plasma membrane abundance of the sulfatide-binding protein NF155 links glycosphingolipid imbalances to demyelination
Myelin is a multilayered membrane that tightly wraps neuronal axons, enabling efficient, high-speed signal propagation. The axon and myelin sheath form tight contacts, mediated by specific plasma membrane proteins and lipids, and disruption of these contacts causes devastating demyelinating diseases...
Autores principales: | McKie, Shannon J., Nicholson, Alex S., Smith, Emily, Fawke, Stuart, Caroe, Eve R., Williamson, James C., Butt, Benjamin G., Kolářová, Denisa, Peterka, Ondřej, Holčapek, Michal, Lehner, Paul J., Graham, Stephen C., Deane, Janet E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083573/ https://www.ncbi.nlm.nih.gov/pubmed/36996106 http://dx.doi.org/10.1073/pnas.2218823120 |
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