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Altered plasma membrane abundance of the sulfatide-binding protein NF155 links glycosphingolipid imbalances to demyelination

Myelin is a multilayered membrane that tightly wraps neuronal axons, enabling efficient, high-speed signal propagation. The axon and myelin sheath form tight contacts, mediated by specific plasma membrane proteins and lipids, and disruption of these contacts causes devastating demyelinating diseases...

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Detalles Bibliográficos
Autores principales: McKie, Shannon J., Nicholson, Alex S., Smith, Emily, Fawke, Stuart, Caroe, Eve R., Williamson, James C., Butt, Benjamin G., Kolářová, Denisa, Peterka, Ondřej, Holčapek, Michal, Lehner, Paul J., Graham, Stephen C., Deane, Janet E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083573/
https://www.ncbi.nlm.nih.gov/pubmed/36996106
http://dx.doi.org/10.1073/pnas.2218823120

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