Impact of taxane-based chemotherapeutics on male reproductive function

Men and boys with cancer treated with chemotherapy are known to have reduced fertility following their treatment. This is because some chemotherapy drugs can damage the cells in the testicles that make sperm. This study found there is limited information available on the effect of one group of chemo...

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Detalles Bibliográficos
Autores principales: Kanodia, Charvi, Rimmer, Michael P, Duffin, Kathleen, Mitchell, Rod T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083651/
https://www.ncbi.nlm.nih.gov/pubmed/36795651
http://dx.doi.org/10.1530/RAF-22-0134
Descripción
Sumario:Men and boys with cancer treated with chemotherapy are known to have reduced fertility following their treatment. This is because some chemotherapy drugs can damage the cells in the testicles that make sperm. This study found there is limited information available on the effect of one group of chemotherapy drugs, called taxanes, on testicular function and fertility. More studies are needed to aid clinicians in advising patients on how this taxane-based chemotherapy may affect their future fertility.

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