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A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences

OBJECTIVE: To design a deep learning model based on multimodal magnetic resonance image (MRI) sequences for automatic parotid neoplasm classification, and to improve the diagnostic decision‐making in clinical settings. METHODS: First, multimodal MRI sequences were collected from 266 patients with pa...

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Autores principales: Liu, Xu, Pan, Yucheng, Zhang, Xin, Sha, Yongfang, Wang, Shihui, Li, Hongzhe, Liu, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083903/
https://www.ncbi.nlm.nih.gov/pubmed/35575610
http://dx.doi.org/10.1002/lary.30154
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author Liu, Xu
Pan, Yucheng
Zhang, Xin
Sha, Yongfang
Wang, Shihui
Li, Hongzhe
Liu, Jianping
author_facet Liu, Xu
Pan, Yucheng
Zhang, Xin
Sha, Yongfang
Wang, Shihui
Li, Hongzhe
Liu, Jianping
author_sort Liu, Xu
collection PubMed
description OBJECTIVE: To design a deep learning model based on multimodal magnetic resonance image (MRI) sequences for automatic parotid neoplasm classification, and to improve the diagnostic decision‐making in clinical settings. METHODS: First, multimodal MRI sequences were collected from 266 patients with parotid neoplasms, and an artificial intelligence (AI)‐based deep learning model was designed from scratch, combining the image classification network of Resnet and the Transformer network of Natural language processing. Second, the effectiveness of the deep learning model was improved through the multi‐modality fusion of MRI sequences, and the fusion strategy of various MRI sequences was optimized. In addition, we compared the effectiveness of the model in the parotid neoplasm classification with experienced radiologists. RESULTS: The deep learning model delivered reliable outcomes in differentiating benign and malignant parotid neoplasms. The model, which was trained by the fusion of T2‐weighted, postcontrast T1‐weighted, and diffusion‐weighted imaging (b = 1000 s/mm(2)), produced the best result, with an accuracy score of 0.85, an area under the receiver operator characteristic (ROC) curve of 0.96, a sensitivity score of 0.90, and a specificity score of 0.84. In addition, the multi‐modal paradigm exhibited reliable outcomes in diagnosing the pleomorphic adenoma and the Warthin tumor, but not in the identification of the basal cell adenoma. CONCLUSION: An accurate and efficient AI based classification model was produced to classify parotid neoplasms, resulting from the fusion of multimodal MRI sequences. The effectiveness certainly outperformed the model with single MRI images or single MRI sequences as input, and potentially, experienced radiologists. LEVEL OF EVIDENCE: 3 Laryngoscope, 133:327–335, 2023
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spelling pubmed-100839032023-04-11 A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences Liu, Xu Pan, Yucheng Zhang, Xin Sha, Yongfang Wang, Shihui Li, Hongzhe Liu, Jianping Laryngoscope Head and Neck OBJECTIVE: To design a deep learning model based on multimodal magnetic resonance image (MRI) sequences for automatic parotid neoplasm classification, and to improve the diagnostic decision‐making in clinical settings. METHODS: First, multimodal MRI sequences were collected from 266 patients with parotid neoplasms, and an artificial intelligence (AI)‐based deep learning model was designed from scratch, combining the image classification network of Resnet and the Transformer network of Natural language processing. Second, the effectiveness of the deep learning model was improved through the multi‐modality fusion of MRI sequences, and the fusion strategy of various MRI sequences was optimized. In addition, we compared the effectiveness of the model in the parotid neoplasm classification with experienced radiologists. RESULTS: The deep learning model delivered reliable outcomes in differentiating benign and malignant parotid neoplasms. The model, which was trained by the fusion of T2‐weighted, postcontrast T1‐weighted, and diffusion‐weighted imaging (b = 1000 s/mm(2)), produced the best result, with an accuracy score of 0.85, an area under the receiver operator characteristic (ROC) curve of 0.96, a sensitivity score of 0.90, and a specificity score of 0.84. In addition, the multi‐modal paradigm exhibited reliable outcomes in diagnosing the pleomorphic adenoma and the Warthin tumor, but not in the identification of the basal cell adenoma. CONCLUSION: An accurate and efficient AI based classification model was produced to classify parotid neoplasms, resulting from the fusion of multimodal MRI sequences. The effectiveness certainly outperformed the model with single MRI images or single MRI sequences as input, and potentially, experienced radiologists. LEVEL OF EVIDENCE: 3 Laryngoscope, 133:327–335, 2023 John Wiley & Sons, Inc. 2022-05-16 2023-02 /pmc/articles/PMC10083903/ /pubmed/35575610 http://dx.doi.org/10.1002/lary.30154 Text en © 2022 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Head and Neck
Liu, Xu
Pan, Yucheng
Zhang, Xin
Sha, Yongfang
Wang, Shihui
Li, Hongzhe
Liu, Jianping
A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences
title A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences
title_full A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences
title_fullStr A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences
title_full_unstemmed A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences
title_short A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences
title_sort deep learning model for classification of parotid neoplasms based on multimodal magnetic resonance image sequences
topic Head and Neck
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083903/
https://www.ncbi.nlm.nih.gov/pubmed/35575610
http://dx.doi.org/10.1002/lary.30154
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