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A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences
OBJECTIVE: To design a deep learning model based on multimodal magnetic resonance image (MRI) sequences for automatic parotid neoplasm classification, and to improve the diagnostic decision‐making in clinical settings. METHODS: First, multimodal MRI sequences were collected from 266 patients with pa...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083903/ https://www.ncbi.nlm.nih.gov/pubmed/35575610 http://dx.doi.org/10.1002/lary.30154 |
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author | Liu, Xu Pan, Yucheng Zhang, Xin Sha, Yongfang Wang, Shihui Li, Hongzhe Liu, Jianping |
author_facet | Liu, Xu Pan, Yucheng Zhang, Xin Sha, Yongfang Wang, Shihui Li, Hongzhe Liu, Jianping |
author_sort | Liu, Xu |
collection | PubMed |
description | OBJECTIVE: To design a deep learning model based on multimodal magnetic resonance image (MRI) sequences for automatic parotid neoplasm classification, and to improve the diagnostic decision‐making in clinical settings. METHODS: First, multimodal MRI sequences were collected from 266 patients with parotid neoplasms, and an artificial intelligence (AI)‐based deep learning model was designed from scratch, combining the image classification network of Resnet and the Transformer network of Natural language processing. Second, the effectiveness of the deep learning model was improved through the multi‐modality fusion of MRI sequences, and the fusion strategy of various MRI sequences was optimized. In addition, we compared the effectiveness of the model in the parotid neoplasm classification with experienced radiologists. RESULTS: The deep learning model delivered reliable outcomes in differentiating benign and malignant parotid neoplasms. The model, which was trained by the fusion of T2‐weighted, postcontrast T1‐weighted, and diffusion‐weighted imaging (b = 1000 s/mm(2)), produced the best result, with an accuracy score of 0.85, an area under the receiver operator characteristic (ROC) curve of 0.96, a sensitivity score of 0.90, and a specificity score of 0.84. In addition, the multi‐modal paradigm exhibited reliable outcomes in diagnosing the pleomorphic adenoma and the Warthin tumor, but not in the identification of the basal cell adenoma. CONCLUSION: An accurate and efficient AI based classification model was produced to classify parotid neoplasms, resulting from the fusion of multimodal MRI sequences. The effectiveness certainly outperformed the model with single MRI images or single MRI sequences as input, and potentially, experienced radiologists. LEVEL OF EVIDENCE: 3 Laryngoscope, 133:327–335, 2023 |
format | Online Article Text |
id | pubmed-10083903 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100839032023-04-11 A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences Liu, Xu Pan, Yucheng Zhang, Xin Sha, Yongfang Wang, Shihui Li, Hongzhe Liu, Jianping Laryngoscope Head and Neck OBJECTIVE: To design a deep learning model based on multimodal magnetic resonance image (MRI) sequences for automatic parotid neoplasm classification, and to improve the diagnostic decision‐making in clinical settings. METHODS: First, multimodal MRI sequences were collected from 266 patients with parotid neoplasms, and an artificial intelligence (AI)‐based deep learning model was designed from scratch, combining the image classification network of Resnet and the Transformer network of Natural language processing. Second, the effectiveness of the deep learning model was improved through the multi‐modality fusion of MRI sequences, and the fusion strategy of various MRI sequences was optimized. In addition, we compared the effectiveness of the model in the parotid neoplasm classification with experienced radiologists. RESULTS: The deep learning model delivered reliable outcomes in differentiating benign and malignant parotid neoplasms. The model, which was trained by the fusion of T2‐weighted, postcontrast T1‐weighted, and diffusion‐weighted imaging (b = 1000 s/mm(2)), produced the best result, with an accuracy score of 0.85, an area under the receiver operator characteristic (ROC) curve of 0.96, a sensitivity score of 0.90, and a specificity score of 0.84. In addition, the multi‐modal paradigm exhibited reliable outcomes in diagnosing the pleomorphic adenoma and the Warthin tumor, but not in the identification of the basal cell adenoma. CONCLUSION: An accurate and efficient AI based classification model was produced to classify parotid neoplasms, resulting from the fusion of multimodal MRI sequences. The effectiveness certainly outperformed the model with single MRI images or single MRI sequences as input, and potentially, experienced radiologists. LEVEL OF EVIDENCE: 3 Laryngoscope, 133:327–335, 2023 John Wiley & Sons, Inc. 2022-05-16 2023-02 /pmc/articles/PMC10083903/ /pubmed/35575610 http://dx.doi.org/10.1002/lary.30154 Text en © 2022 The Authors. The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Head and Neck Liu, Xu Pan, Yucheng Zhang, Xin Sha, Yongfang Wang, Shihui Li, Hongzhe Liu, Jianping A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences |
title | A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences |
title_full | A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences |
title_fullStr | A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences |
title_full_unstemmed | A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences |
title_short | A Deep Learning Model for Classification of Parotid Neoplasms Based on Multimodal Magnetic Resonance Image Sequences |
title_sort | deep learning model for classification of parotid neoplasms based on multimodal magnetic resonance image sequences |
topic | Head and Neck |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10083903/ https://www.ncbi.nlm.nih.gov/pubmed/35575610 http://dx.doi.org/10.1002/lary.30154 |
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