Cargando…
Results and insights from a phase I clinical trial of Lomecel‐B for Alzheimer's disease
HYPOTHESIS: We hypothesized that Lomecel‐B, an allogeneic medicinal signaling cell (MSC) therapeutic candidate for Alzheimer's disease (AD), is safe and potentially disease‐modifying via pleiotropic mechanisms of action. KEY PREDICTIONS: We prospectively tested the predictions that Lomecel‐B ad...
Autores principales: | Brody, Mark, Agronin, Marc, Herskowitz, Brad J., Bookheimer, Susan Y., Small, Gary W., Hitchinson, Benjamin, Ramdas, Kevin, Wishard, Tyler, McInerney, Katalina Fernández, Vellas, Bruno, Sierra, Felipe, Jiang, Zhijie, Mcclain‐Moss, Lisa, Perez, Carmen, Fuquay, Ana, Rodriguez, Savannah, Hare, Joshua M., Oliva, Anthony A., Baumel, Bernard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084163/ https://www.ncbi.nlm.nih.gov/pubmed/35357079 http://dx.doi.org/10.1002/alz.12651 |
Ejemplares similares
-
A Phase I Trial Assessing Lomecel-B Infusion in Individuals with Alzheimer’s Disease: Study Design and Rationale
por: Ramdas, Kevin, et al.
Publicado: (2021) -
A Phase 2b Clinical Trial Assessing Lomecel-B Infusion in Individuals with Aging Frailty: Study Design and Rationale
por: Ramdas, Kevin, et al.
Publicado: (2021) -
BLOOD-BASED BIOMARKER CHANGES IN A PHASE 2B TRIAL ASSESSING LOMECEL-B IN OLDER ADULTS WITH FRAILTY
por: Ramdas, Kevin, et al.
Publicado: (2022) -
Intramyocardial cell-based therapy with Lomecel-B during bidirectional cavopulmonary anastomosis for hypoplastic left heart syndrome: the ELPIS phase I trial
por: Kaushal, Sunjay, et al.
Publicado: (2023) -
Evaluation of a dental nurse-led triage system in a private dental practice during the COVID-19 pandemic
por: Cowell, Angela, et al.
Publicado: (2021)