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Excess vitamin a might contribute to submucous clefting by inhibiting WNT‐mediated bone formation

OBJECTIVES: Cleft lip and/or palate (CLP) is a common craniofacial birth defect caused by genetic as well as environmental factors. The phenotypic spectrum of CLP also includes submucous clefts with a defect in the palatal bone. To elucidate the contribution of vitamin A, we evaluated the effects of...

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Detalles Bibliográficos
Autores principales: Krutzen, Charlotte Lucienne Jacqueline Maria, Roa, Laury A., Bloemen, Marjon, Von den Hoff, Johannes W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084165/
https://www.ncbi.nlm.nih.gov/pubmed/35716278
http://dx.doi.org/10.1111/ocr.12594