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Biomimetic liposomal nanozymes improve breast cancer chemotherapy with enhanced penetration and alleviated hypoxia

BACKGROUND: Doxorubicin (Dox) has been recommended in clinical guidelines for the standard-of-care treatment of breast cancer. However, Dox therapy faces challenges such as hypoxia, acidosis, H(2)O(2)-rich conditions and condensed extracellular matrix in TME as well as low targeted ability. METHODS:...

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Detalles Bibliográficos
Autores principales: Li, Juanjuan, Gong, Chunai, Chen, Xinlu, Guo, Huanhuan, Tai, Zongguang, Ding, Nan, Gao, Shen, Gao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084658/
https://www.ncbi.nlm.nih.gov/pubmed/37038165
http://dx.doi.org/10.1186/s12951-023-01874-7