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Clinical and genetic characteristics in a central-southern Chinese cohort of early-onset Alzheimer's disease

BACKGROUND: Mutations in the presenilin-1 (PSEN1), presenilin-2 (PSEN2), and amyloid precursor protein (APP) genes have been commonly identified in early-onset Alzheimer's disease (EOAD). Some of the mutations in the three causative genes, especially the PSEN1 gene, result in variable phenotype...

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Detalles Bibliográficos
Autores principales: Liang, Zhihou, Wu, Yan, Li, Chuanzhou, Liu, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084792/
https://www.ncbi.nlm.nih.gov/pubmed/37051054
http://dx.doi.org/10.3389/fneur.2023.1119326

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