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Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region

PURPOSE: We performed an assessment of the rejuvenation effect of an amino acid and hyaluronic acid mixture in the periorbital area. METHODS: A total of 23 of the 35 participants completed all application sessions and measurements. These 23 women were aged 30–55 years. A hyaluronic acid and amino ac...

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Autores principales: Kabakci, Ayse Gul, Bozkır, Dursun Murat, Cengizler, Çağlar, Sire Eren, Dilek, Bozkır, Memduha Gülhal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084865/
https://www.ncbi.nlm.nih.gov/pubmed/37051585
http://dx.doi.org/10.2147/CCID.S406173
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author Kabakci, Ayse Gul
Bozkır, Dursun Murat
Cengizler, Çağlar
Sire Eren, Dilek
Bozkır, Memduha Gülhal
author_facet Kabakci, Ayse Gul
Bozkır, Dursun Murat
Cengizler, Çağlar
Sire Eren, Dilek
Bozkır, Memduha Gülhal
author_sort Kabakci, Ayse Gul
collection PubMed
description PURPOSE: We performed an assessment of the rejuvenation effect of an amino acid and hyaluronic acid mixture in the periorbital area. METHODS: A total of 23 of the 35 participants completed all application sessions and measurements. These 23 women were aged 30–55 years. A hyaluronic acid and amino acid mixture was injected into the participants’ periorbital area. Three sessions of application with 15-day intervals were undertaken. Subjects’ age, height, weight, smoking status, and sport participation were recorded. A photonumeric dark circle scale and Fitzpatrick’s periorbital wrinkling classification were used for evaluation of dark circles and wrinkles in the periorbital area. Anatomical measurements (height of upper and lower eyelids) were done using ImageJ and a skin-analysis system (Observ 520). RESULTS: The 23 women had a mean age of 42.46±9.33 years, mean height 164.46±4.96 cm, and mean weight 63.94±8.26 kg. Before the sessions, the mean heights of the upper eyelids were 1.24±013 cm (right) and 1.21±013 cm (left), while those of the lower eyelids were 0.98±014 cm (right) and 0.97±0.17 cm (left). One month after the third session, mean upper-eyelid heights were 1.30±0.09 cm (right) and 1.28±0.11 cm (left) and lower-eyelid ones 1.02±0.11 cm (right) and 1.02±0.13 cm (left). Dark-circle and wrinkle-scale scores showed significantly positive results between before the sessions and 1 month after the third session. CONCLUSION: A hyaluronic acid and amino acid mixture can be used to rejuvenation of the periorbital area in women aged 30–55 years.
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spelling pubmed-100848652023-04-11 Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region Kabakci, Ayse Gul Bozkır, Dursun Murat Cengizler, Çağlar Sire Eren, Dilek Bozkır, Memduha Gülhal Clin Cosmet Investig Dermatol Original Research PURPOSE: We performed an assessment of the rejuvenation effect of an amino acid and hyaluronic acid mixture in the periorbital area. METHODS: A total of 23 of the 35 participants completed all application sessions and measurements. These 23 women were aged 30–55 years. A hyaluronic acid and amino acid mixture was injected into the participants’ periorbital area. Three sessions of application with 15-day intervals were undertaken. Subjects’ age, height, weight, smoking status, and sport participation were recorded. A photonumeric dark circle scale and Fitzpatrick’s periorbital wrinkling classification were used for evaluation of dark circles and wrinkles in the periorbital area. Anatomical measurements (height of upper and lower eyelids) were done using ImageJ and a skin-analysis system (Observ 520). RESULTS: The 23 women had a mean age of 42.46±9.33 years, mean height 164.46±4.96 cm, and mean weight 63.94±8.26 kg. Before the sessions, the mean heights of the upper eyelids were 1.24±013 cm (right) and 1.21±013 cm (left), while those of the lower eyelids were 0.98±014 cm (right) and 0.97±0.17 cm (left). One month after the third session, mean upper-eyelid heights were 1.30±0.09 cm (right) and 1.28±0.11 cm (left) and lower-eyelid ones 1.02±0.11 cm (right) and 1.02±0.13 cm (left). Dark-circle and wrinkle-scale scores showed significantly positive results between before the sessions and 1 month after the third session. CONCLUSION: A hyaluronic acid and amino acid mixture can be used to rejuvenation of the periorbital area in women aged 30–55 years. Dove 2023-04-06 /pmc/articles/PMC10084865/ /pubmed/37051585 http://dx.doi.org/10.2147/CCID.S406173 Text en © 2023 Kabakci et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Kabakci, Ayse Gul
Bozkır, Dursun Murat
Cengizler, Çağlar
Sire Eren, Dilek
Bozkır, Memduha Gülhal
Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region
title Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region
title_full Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region
title_fullStr Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region
title_full_unstemmed Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region
title_short Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region
title_sort assessing the rejuvenation effectiveness of a hyaluronic acid and amino acid mixture in the periorbital region
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084865/
https://www.ncbi.nlm.nih.gov/pubmed/37051585
http://dx.doi.org/10.2147/CCID.S406173
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