Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment

Human lung adenosquamous cell carcinoma (LUAS), containing both adenomatous and squamous pathologies, harbors strong plasticity and is significantly associated with poor prognosis. We established an up-to-date comprehensive genomic and transcriptomic landscape of LUAS in 109 Chinese specimens and de...

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Detalles Bibliográficos
Autores principales: Tang, Shijie, Xue, Yun, Qin, Zhen, Fang, Zhaoyuan, Sun, Yihua, Yuan, Chongzhe, Pan, Yunjian, Zhao, Yue, Tong, Xinyuan, Zhang, Jian, Huang, Hsinyi, Chen, Yuting, Hu, Liang, Huang, Dasong, Wang, Ruiqi, Zou, Weiguo, Li, Yuan, Thomas, Roman K, Ventura, Andrea, Wong, Kwok-Kin, Chen, Haiquan, Chen, Luonan, Ji, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084920/
https://www.ncbi.nlm.nih.gov/pubmed/37051524
http://dx.doi.org/10.1093/nsr/nwad028

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